tert-Butyl (3-(4-bromophenyl)oxetan-3-yl)carbamate
≥95%
Reagent
Code: #148802
CAS Number
1279090-24-2
blur_circular Chemical Specifications
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Molecular Information
Weight
328.20 g/mol
Formula
C₁₄H₁₈BrNO₃
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Registry Numbers
MDL Number
MFCD22628720
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. The bromophenyl group allows for further functionalization via cross-coupling reactions such as Suzuki or Heck reactions, enabling rapid diversification of molecular structure. The oxetane ring contributes to metabolic stability and improved pharmacokinetic properties in drug candidates. The tert-butyl carbamate (Boc) group serves as a protected amine, facilitating stepwise assembly in multi-step syntheses. Commonly employed in medicinal chemistry for optimizing lead compounds in oncology and CNS drug discovery programs.
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