(S)-2-(Benzo[b]thiophen-2-yl)-4-isopropyl-4,5-dihydrooxazole
97% 99%ee
Reagent
Code: #236988
CAS Number
541549-94-4
blur_circular Chemical Specifications
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Molecular Information
Weight
245.34 g/mol
Formula
C₁₄H₁₅NOS
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a chiral auxiliary in asymmetric synthesis, this compound plays a key role in controlling stereochemistry during the formation of carbon-carbon bonds. It is commonly employed in enantioselective alkylation reactions, especially in the synthesis of complex natural products and pharmaceutical intermediates. The oxazoline ring coordinates with metal catalysts, enhancing stereoselectivity. After serving its purpose, the auxiliary can be cleaved under mild conditions, leaving the desired chiral product intact. Its stability under various reaction conditions and ease of removal make it valuable in multi-step organic synthesis.
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