Tert-butylzinc bromide is primarily used in organic synthesis as a reagent for the introduction of the tert-butyl group into various organic compounds. It is particularly valuable in the formation of carbon-carbon bonds, enabling the construction of complex molecular structures. This compound is often employed in the synthesis of pharmaceuticals, where the tert-butyl group can enhance the stability, bioavailability, or activity of the drug molecules. Additionally, it finds application in materials science for the modification of polymers and other materials, where the tert-butyl group can impart specific physical or chemical properties. Its reactivity with a wide range of organic substrates makes it a versatile tool in both academic research and industrial chemistry.