1-Adamantylzinc bromide is primarily utilized in organic synthesis as a reagent for introducing the adamantyl group into various organic molecules. The adamantyl group is known for its steric bulk and stability, making it valuable in the development of pharmaceuticals and materials with enhanced properties. This compound is particularly effective in cross-coupling reactions, such as Negishi coupling, where it facilitates the formation of carbon-carbon bonds between adamantyl and aryl or alkyl groups. Its application is crucial in the synthesis of complex organic compounds, including potential drug candidates, where the adamantyl moiety can improve metabolic stability and bioavailability. Additionally, it is used in the preparation of advanced materials, where the incorporation of the adamantyl group can impart unique structural and thermal characteristics.