Used as a reagent in organic synthesis, particularly in cross-coupling reactions such as Negishi coupling, where it transfers the cyclobutyl group to various organic electrophiles. Its reactivity makes it valuable for constructing carbon-carbon bonds in the development of pharmaceuticals and complex organic molecules. Commonly employed in the synthesis of cyclobutane-containing compounds, which are of interest in medicinal chemistry due to their metabolic stability and three-dimensional structure. Often generated and used in situ due to its sensitivity to air and moisture.