Cyclopropylzinc bromide is widely used in organic synthesis as a versatile reagent for introducing the cyclopropyl group into various molecular frameworks. It is particularly valuable in cross-coupling reactions, such as Negishi coupling, where it facilitates the formation of carbon-carbon bonds with aryl or vinyl halides. This reagent is also employed in the synthesis of complex natural products and pharmaceuticals, where the cyclopropyl moiety is a key structural element. Its stability and reactivity make it a preferred choice for constructing cyclopropane-containing compounds, which are often explored for their biological activity and unique chemical properties. Additionally, it is used in asymmetric synthesis to create chiral cyclopropyl derivatives, which are important in the development of enantioselective catalysts and drugs.