Azidotributyltin(IV) is primarily used in organic synthesis as a reagent for the introduction of azide groups into various chemical compounds. It plays a significant role in click chemistry, particularly in the synthesis of triazoles, which are important in pharmaceutical and material science applications. The compound is also utilized in polymer chemistry to modify polymers by incorporating azide functionalities, enhancing their properties for specific industrial uses. Additionally, it finds application in the preparation of organotin compounds, which are used as stabilizers in PVC production and as biocides in antifouling paints. Its reactivity with organic substrates makes it valuable in the development of new materials and bioactive molecules. Due to its high toxicity, proper handling and disposal precautions are essential.