Tributyl-(3-chloropyridin-2-yl)stannane is primarily used in organic synthesis as a reagent for introducing the 3-chloropyridin-2-yl group into various organic compounds. It is particularly valuable in Stille coupling reactions, a type of cross-coupling reaction that forms carbon-carbon bonds, which is essential in the synthesis of complex molecules like pharmaceuticals, agrochemicals, and advanced materials. Its organotin structure facilitates efficient and selective coupling with aryl or vinyl halides, making it a useful tool in the development of biologically active compounds and functional materials. Additionally, it is employed in the preparation of heterocyclic compounds, which are key intermediates in drug discovery and material science.