2-Fluoro-5-(tributylstannyl)pyridine
≥97%
Reagent
Code: #129639
CAS Number
1025687-41-5
blur_circular Chemical Specifications
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Molecular Information
Weight
386.1 g/mol
Formula
C₁₇H₃₀FNSn
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Registry Numbers
MDL Number
MFCD07787406
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in palladium-catalyzed cross-coupling reactions such as Stille coupling. The presence of the tributylstannyl group allows for efficient formation of carbon-carbon bonds, enabling the introduction of the 2-fluoropyridine moiety into more complex molecules. This is especially valuable in drug development for creating analogs with enhanced biological activity or improved metabolic stability. Commonly applied in the preparation of kinase inhibitors and other bioactive heterocyclic compounds.
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