Used as a reagent in organic synthesis, particularly for introducing trimethylsilyl groups into molecules, which can enhance stability or alter reactivity. It is also employed in the preparation of silyl esters, which are useful intermediates in various chemical reactions. Additionally, it finds application in modifying surfaces or materials to impart hydrophobic properties. In pharmaceutical research, it serves as a building block for synthesizing complex molecules. Its role in protecting functional groups during multi-step synthesis is another key application.