Used primarily as an intermediate in the synthesis of organophosphorus compounds, particularly in the production of flame retardants, plasticizers, and synthetic phospholipids for pharmaceutical applications such as targeted drug delivery systems (e.g., liposomes). Its reactivity facilitates the introduction of phosphorus-containing groups into larger molecules, enhancing thermal stability and fire resistance in polymers, as well as enabling the formation of phosphodiester bonds in laboratory synthesis of biomolecules with phosphate structures. Also employed in specialty surfactants, synthetic lubricants, and cosmetic formulations to improve skin permeability and penetration in skincare products, owing to its hydrophobic decyl chains and reactive chlorine site. Handling requires caution due to potential hydrolysis, which may release corrosive byproducts.