2-(Diphenylphosphino)acetic acid is widely used as a ligand in coordination chemistry, particularly in the formation of metal complexes. Its phosphine and carboxylic acid functional groups make it effective in stabilizing transition metals, enabling its application in catalytic processes such as hydrogenation, cross-coupling reactions, and olefin polymerization. In organic synthesis, it serves as a key component in asymmetric catalysis, contributing to the production of chiral molecules with high enantioselectivity. Additionally, it is utilized in the development of advanced materials, including metal-organic frameworks (MOFs), due to its ability to coordinate with metal ions and create structured networks. Its versatility also extends to biochemical research, where it aids in the study of enzyme mechanisms and metal ion interactions in biological systems.