Trimethylboroxine is primarily used in organic synthesis as a reagent for the preparation of boron-containing compounds. It serves as a key intermediate in the production of boronic acids and esters, which are essential in Suzuki-Miyaura cross-coupling reactions. These reactions are widely employed in the pharmaceutical industry for the synthesis of complex organic molecules, including drugs and bioactive compounds. Additionally, it is utilized in the development of advanced materials, such as polymers and coatings, where boron-based additives enhance thermal stability and flame retardancy. In research, it is also explored for its potential in catalysis and as a precursor for boron-doped materials in electronics and energy storage applications.