Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of nonsteroidal anti-inflammatory drugs (NSAIDs) for alleviating pain, fever, and inflammation, and other bioactive molecules. The trifluoromethoxy group enhances metabolic stability, increases lipophilicity for improved absorption, and supports modulation of biological activity, making it valuable in medicinal chemistry for optimizing drug potency, efficacy, cell membrane penetration, and targeted enzyme inhibition. Also employed in the preparation of chiral building blocks for asymmetric synthesis, aiding in the creation of enantiomerically pure compounds.