(3aR,4R,5R,6aS)-5-Hydroxy-4-((R)-3-hydroxy-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one
95%
Reagent
Code: #228748
CAS Number
145667-75-0
blur_circular Chemical Specifications
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Molecular Information
Weight
304.38 g/mol
Formula
C₁₈H₂₄O₄
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Registry Numbers
MDL Number
MFCD05865275
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Physical Properties
Melting Point
69-71 °C
Boiling Point
523.0±35.0 °C(Predicted)
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Storage & Handling
Density
1.202 g/cm3
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of prostaglandin analogs, particularly those targeting ophthalmic conditions such as glaucoma. It plays a critical role in the development of drugs that reduce intraocular pressure by enhancing uveoscleral outflow of aqueous humor. Its stereochemistry allows for high selectivity and potency in binding to prostaglandin receptors, improving therapeutic efficacy while minimizing side effects. Also investigated for potential applications in treating cardiovascular diseases due to its influence on smooth muscle relaxation and vascular tone.
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