Used as a key intermediate in the synthesis of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly in the development of selective COX-2 inhibitors. Its structure allows for effective binding and modulation of cyclooxygenase enzymes, contributing to anti-inflammatory, analgesic, and antipyretic effects. Commonly employed in medicinal chemistry for optimizing drug candidates targeting chronic inflammatory conditions such as arthritis. Also utilized in research settings to explore structure-activity relationships in aryl ethynyl derivatives.