Methyl 4-(trifluoromethyl)benzoate
99%
Reagent
Code: #205201
Alias
Methyl 4-(trifluoromethyl)benzoate
Methyl para-trifluoromethylbenzoate
CAS Number
2967-66-0
science Other reagents with same CAS 2967-66-0
blur_circular Chemical Specifications
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Molecular Information
Weight
204.15 g/mol
Formula
C₉H₇F₃O₂
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Registry Numbers
MDL Number
MFCD00042324
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Physical Properties
Melting Point
13-14 °C(lit.)
Boiling Point
94-95 °C21 mm Hg(lit.)
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Storage & Handling
Density
1.268 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of compounds with enhanced metabolic stability and lipophilicity due to the presence of the trifluoromethyl group. Commonly employed in medicinal chemistry for the preparation of bioactive molecules, including anti-inflammatory and central nervous system agents. Also utilized in the design of fluorinated analogs in structure-activity relationship (SAR) studies to improve potency and selectivity. Its ester functionality allows for easy transformation into carboxylic acids, amides, or alcohols, making it a versatile building block in organic synthesis.
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