DAMGO is primarily used in scientific research to study the mechanisms of opioid receptors, particularly the mu-opioid receptor. It is a selective agonist for this receptor, making it a valuable tool for understanding pain pathways, addiction, and the effects of opioids on the nervous system. Researchers use DAMGO to investigate the physiological and behavioral responses triggered by mu-opioid receptor activation. It is also employed in experiments exploring potential treatments for pain management and opioid dependence, as well as in studies aimed at developing safer and more effective analgesic drugs.