16-phenoxy PGF2α ethyl amide is a synthetic analog of prostaglandin F2α, primarily used as a research reagent in ophthalmology for studying the management of glaucoma and ocular hypertension. It functions by reducing intraocular pressure (IOP) through increasing the outflow of aqueous humor from the eye, showing potential in preventing optic nerve damage and preserving vision in preclinical models. It is also utilized in veterinary research for similar ocular applications in animals. Its prostaglandin analog properties provide targeted action on FP receptors with minimal systemic side effects, making it suitable for long-term experimental studies. Human clinical use remains under investigation.