Bexarotene is a synthetic retinoid (chemical formula: C₂₄H₂₈O₂, CAS: 153559-49-0) and a selective agonist for retinoid X receptors (RXRs). It is primarily used in the treatment of cutaneous T-cell lymphoma (CTCL), a type of non-Hodgkin lymphoma affecting the skin, particularly in patients with refractory or relapsed disease. Bexarotene works by binding to RXRs, which regulate gene expression involved in cell growth, differentiation, and apoptosis, thereby inhibiting the proliferation of cancer cells. It is available as an oral capsule or topical gel formulation. Off-label uses include investigations for other malignancies like breast cancer and psoriasis due to its modulation of cell growth. As a specialty pharmaceutical chemical, it requires careful handling. Patients are monitored for side effects such as hyperlipidemia, hypothyroidism, and hepatotoxicity.