Maytansinol
95%
Reagent
Code: #51232
Alias
Ansamitocin; Ansamitocin P 0; Antibiotic C 15003P0; NSC 239386;
CAS Number
57103-68-1
Properties
Chloroform (Slightly), Methanol (Slightly)
science Other reagents with same CAS 57103-68-1
blur_circular Chemical Specifications
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Molecular Information
Weight
565.05 g/mol
Formula
C₂₈H₃₇ClN₂O₈
thermostat
Physical Properties
Melting Point
>153ºC (dec.)
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Storage & Handling
Storage
2-8℃, inert gas atmosphere
description Product Description
Maytansinol is primarily used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. Its potent cytotoxic properties make it an effective payload in these conjugates, where it is attached to monoclonal antibodies that specifically recognize and bind to cancer cells. This targeted approach allows for the delivery of the cytotoxic agent directly to tumor cells, minimizing damage to healthy tissues and reducing systemic side effects. Maytansinol-based ADCs have shown promise in treating various cancers, including breast cancer and lymphoma, by inhibiting cell division and inducing apoptosis in malignant cells. Its application in precision medicine continues to be a significant area of research in oncology.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Light yellow or off-white powder |
| Purity | 95 |
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