Used primarily in the treatment of advanced breast and endometrial cancers, it works by counteracting estrogen effects and slowing tumor growth.

It is also prescribed to manage appetite loss and weight reduction in patients with cancer or HIV/AIDS, helping improve nutritional intake and quality of life.

Additionally, it may be used as a hormonal therapy for certain gynecological disorders due to its progestational activity, including irregular menstrual cycles, abnormal uterine bleeding, control of menstrual cycles, or treatment of infertility related to hormonal imbalances.

It is also used in veterinary medicine, particularly in cats and dogs, to treat skin conditions or control hormone-related behaviors.