JNJ-26854165

10mM in DMSO

Reagent Code: #201297
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CAS Number 881202-45-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 328.41 g/mol
Formula C₂₁H₂₀N₄
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research for the treatment of various cancers, particularly hematologic malignancies such as leukemia and lymphoma. It functions as a p53 activator by inhibiting MDM2, a protein that normally suppresses p53 activity. By restoring p53 function, it promotes cancer cell apoptosis and inhibits tumor growth. Also investigated for solid tumors where p53 pathways are intact but suppressed. Shows potential in combination therapies with chemotherapy or targeted agents to enhance anti-tumor effects. Its development supports the study of targeted cancer treatments that exploit tumor suppressor pathways.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿5,620.00

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