JNJ-26854165
10mM in DMSO
Reagent
Code: #201297
CAS Number
881202-45-5
blur_circular Chemical Specifications
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Molecular Information
Weight
328.41 g/mol
Formula
C₂₁H₂₀N₄
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Storage & Handling
Storage
-20°C
description Product Description
Used in research for the treatment of various cancers, particularly hematologic malignancies such as leukemia and lymphoma. It functions as a p53 activator by inhibiting MDM2, a protein that normally suppresses p53 activity. By restoring p53 function, it promotes cancer cell apoptosis and inhibits tumor growth. Also investigated for solid tumors where p53 pathways are intact but suppressed. Shows potential in combination therapies with chemotherapy or targeted agents to enhance anti-tumor effects. Its development supports the study of targeted cancer treatments that exploit tumor suppressor pathways.
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