Methyl 4-(3-(1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)propanamido)benzoate
98%
Reagent
Code: #192840
CAS Number
848065-95-2
science Other reagents with same CAS 848065-95-2
blur_circular Chemical Specifications
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Molecular Information
Weight
356.37 g/mol
Formula
C₁₉H₂₀N₂O₅
thermostat
Physical Properties
Boiling Point
628.8±55.0 °C(Predicted)
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Storage & Handling
Density
1.315±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used in pharmaceutical research as an intermediate for synthesizing bioactive molecules, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structure enables linkage between target protein ligands and E3 ubiquitin ligase recruiters, facilitating targeted protein degradation. Commonly employed in studies aiming to degrade disease-related proteins, especially in oncology and neurodegenerative disorders. Also utilized in medicinal chemistry for optimizing drug candidates requiring enhanced selectivity and degradation efficiency.
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