(E)-3-Phenyl-1-(4-(pyrimidin-2-yl)piperazin-1-yl)prop-2-en-1-one
90%
Reagent
Code: #181100
CAS Number
1351406-38-6
blur_circular Chemical Specifications
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Molecular Information
Weight
294.35 g/mol
Formula
C₁₇H₁₈N₄O
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Registry Numbers
MDL Number
MFCD00955289
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used in pharmaceutical research as a key intermediate for synthesizing biologically active compounds, particularly in the development of central nervous system agents. Shows potential in the design of serotonin receptor modulators due to the presence of the pyrimidinylpiperazine moiety, which is commonly associated with neuroactive drugs. Also investigated for its role in antimicrobial and anticancer compound development, where the α,β-unsaturated ketone structure enables Michael addition reactions important in drug design. Employed in structure-activity relationship (SAR) studies to optimize pharmacokinetic properties in novel therapeutic candidates.
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