Used in immunological research to modulate T cell activity, particularly targeting regulatory T cells (Tregs) involved in immune suppression. Shows potential in cancer immunotherapy by inhibiting CCR8-mediated recruitment of Tregs to tumor sites, thereby enhancing anti-tumor immune responses. Also investigated for use in inflammatory and autoimmune diseases where CCR8 signaling plays a role in disease progression. Enables selective blockade of chemokine signaling to study immune cell migration and function in vitro and in vivo.