Cilengitide
10mM in DMSO
Reagent
Code: #158010
CAS Number
188968-51-6
blur_circular Chemical Specifications
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Molecular Information
Weight
588.66 g/mol
Formula
C₂₇H₄₀N₈O₇
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Registry Numbers
MDL Number
MFCD04307743
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Storage & Handling
Storage
-20°C
description Product Description
Used in research for cancer treatment, particularly glioblastoma, due to its ability to inhibit integrins involved in tumor angiogenesis and cell survival. It blocks the binding of extracellular matrix proteins to integrin receptors, disrupting blood vessel formation and tumor growth. Though clinical trials showed limited efficacy in late-stage cancers, it remains a tool compound for studying integrin signaling pathways in oncology.
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