CPI-0610
10mM in DMSO
Reagent
Code: #157857
CAS Number
1380087-89-7
blur_circular Chemical Specifications
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Molecular Information
Weight
365.81 g/mol
Formula
C₂₀H₁₆ClN₃O₂
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Storage & Handling
Storage
-20°C
description Product Description
CPI-0610 is a potent and selective inhibitor of the bromodomain and extra-terminal (BET) family of proteins. It is primarily investigated for its therapeutic potential in oncology, particularly in hematologic malignancies. The compound has shown promising activity in clinical trials for patients with myelofibrosis, a type of myeloproliferative neoplasm. By modulating the expression of key oncogenes such as MYC, CPI-0610 helps reduce disease-related symptoms, improve spleen volume, and enhance overall quality of life. Its mechanism allows for epigenetic regulation of gene transcription without causing direct DNA damage, offering a targeted approach with potentially fewer side effects compared to conventional chemotherapy. Research is ongoing to evaluate its use in combination with other agents like JAK inhibitors to increase efficacy.
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