1,3-Bis(2,6-di-i-propylphenyl)imidazolidin-2-ylidene)(2-i-propoxy-5-nitrobenzylidene) ruthenium(II) dichloride Nitro-Grela SiPr
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Widely used as a highly active metathesis catalyst, particularly in ring-closing metathesis (RCM), cross-metathesis (CM), and enyne metathesis reactions. Its enhanced reactivity compared to earlier ruthenium catalysts makes it effective for challenging substrates and sterically hindered olefins. The presence of the nitro group increases initiation speed, enabling faster reaction rates under mild conditions. Commonly employed in the synthesis of complex organic molecules, including natural products and pharmaceuticals, where efficiency and selectivity are critical. Also valued in polymer chemistry for the preparation of functionalized polymers via ring-opening metathesis polymerization (ROMP). The catalyst exhibits good functional group tolerance and can be used with low loading levels, reducing costs and simplifying purification in industrial and academic settings.
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