Tetraphenylsilane is widely used in organic synthesis and materials science due to its stable silicon-centered structure. It serves as a building block in the preparation of advanced silicone-based polymers, offering enhanced thermal and oxidative stability. Its rigid molecular framework makes it valuable in the development of organic light-emitting diodes (OLEDs), where it acts as a host material or intermediate in electron-transport layers. The compound is also employed in the synthesis of liquid crystals and other functional materials requiring high aromatic content and structural rigidity. Additionally, it finds use in research settings for studying silicon–carbon bonding and steric effects in aromatic systems.