2'-O-tert-Butyldimethylsilyl-uridine
95%
Reagent
Code: #40423
CAS Number
54925-71-2
blur_circular Chemical Specifications
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Molecular Information
Weight
358.46 g/mol
Formula
C₁₅H₂₆N₂O₆Si
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Storage & Handling
Storage
2-8℃
description Product Description
This compound is primarily used in the synthesis of modified nucleosides and oligonucleotides, which are essential in the field of nucleic acid research. It serves as a protecting group for the 2'-hydroxyl group in ribonucleosides during chemical reactions, ensuring specific modifications can be made without unwanted side reactions. This is particularly valuable in the development of RNA-based therapeutics, such as siRNA and mRNA, where precise control over nucleotide structure is critical. Additionally, it plays a role in the study of RNA structure and function, enabling researchers to explore the impact of specific modifications on RNA stability and activity. Its application is also seen in the production of nucleotide analogs used in antiviral and anticancer drug development.
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