5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite
98%
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This chemical is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a key building block in the solid-phase synthesis of modified RNA sequences. The protective groups, such as DMT (dimethoxytrityl) and benzoyl, ensure selective reactivity during the stepwise assembly of nucleotides. Its application is crucial in creating customized RNA molecules for studies involving gene expression, RNA interference, and the development of therapeutic agents like antisense oligonucleotides. The methyl modifications enhance the stability and bioavailability of the synthesized RNA, making it valuable for both research and pharmaceutical applications.
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