2'-O-tert-Butyldimethylsilyl-5-methyluridine
95%
Reagent
Code: #40418
CAS Number
922508-26-7
blur_circular Chemical Specifications
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Molecular Information
Weight
372.49 g/mol
Formula
C₁₆H₂₈N₂O₆Si
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Registry Numbers
MDL Number
MFCD28134646
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Storage & Handling
Storage
2-8℃
description Product Description
This chemical is primarily used in the synthesis of modified nucleosides, which are essential building blocks in the development of oligonucleotides. It serves as a protective group for the 2'-hydroxyl position during RNA synthesis, ensuring selective reactivity and stability in complex chemical reactions. This modification is particularly valuable in the production of antisense oligonucleotides and small interfering RNAs (siRNAs), which are crucial in gene silencing and therapeutic applications. Additionally, it plays a role in the study of RNA structure and function, enabling researchers to explore RNA interactions and dynamics in biochemical systems. Its protective properties also make it useful in the development of nucleotide-based drugs and diagnostic tools.
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