2'-Fluoro-2'-deoxy-arabinofuranosyl-adenosine

95%

Reagent Code: #40414
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CAS Number 123334-75-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 269.23 g/mol
Formula C₁₀H₁₂FN₅O₃
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

This compound, known as 2'-fluoro-2'-deoxyarabinofuranosyladenine (2'-F-ara-A), serves as a critical intermediate in the synthesis of fludarabine, a nucleoside analog prodrug primarily used in the treatment of hematological cancers such as chronic lymphocytic leukemia. By mimicking natural nucleosides, it incorporates into the DNA of rapidly dividing cancer cells, causing chain termination and inhibiting DNA synthesis, which halts cell proliferation. Its modified arabinosyl structure enhances stability and selectivity compared to natural counterparts. Additionally, 2'-F-ara-A has been explored in antiviral research for its potential to inhibit viral replication in DNA viruses, including herpesviruses, by targeting viral enzymes and nucleic acid synthesis, offering pathways for developing targeted therapies against viral infections.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿31,221.00
inventory 1mg
10-20 days ฿6,561.00

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