(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
98%
Reagent
Code: #36481
CAS Number
20227-41-2
blur_circular Chemical Specifications
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Molecular Information
Weight
269.23 g/mol
Formula
C₁₀H₁₂FN₅O₃
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Registry Numbers
MDL Number
MFCD12911815
thermostat
Physical Properties
Boiling Point
628.644°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in an inert gas
description Product Description
This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a modified nucleoside, often incorporated into oligonucleotides for research purposes, particularly in studying RNA structure and function. The fluorine substitution enhances its stability and resistance to enzymatic degradation, making it valuable in the development of antisense oligonucleotides and siRNAs for therapeutic applications. Additionally, it is explored in the design of antiviral and anticancer agents, where its unique structure can interfere with viral replication or cancer cell proliferation. Its role in probing biochemical pathways and as a potential therapeutic agent highlights its significance in biomedical research.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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