Used as a key reagent in the synthesis of oligonucleotides, particularly in solid-phase DNA and RNA synthesis. It serves as a phosphitylating agent that enables the formation of phosphite triester linkages between nucleotide units. Its silyl-protected groups enhance stability and solubility in organic solvents, improving coupling efficiency and reducing side reactions. Commonly employed in automated synthesizers for high-yield production of custom sequences used in molecular biology, genetic research, and diagnostic probes.