Used primarily in organic synthesis as a reagent for the preparation of phosphoramidite derivatives, which are crucial intermediates in the synthesis of oligonucleotides. It is particularly valuable in the production of modified nucleic acids and DNA/RNA sequences for research and therapeutic applications. Its role is significant in the development of antisense oligonucleotides, siRNA, and other gene therapy products. Additionally, it finds use in the creation of phosphite ligands for catalysis in various chemical reactions.