UDP-GlcNAz.2Na is widely used in biochemical research for metabolic labeling of glycans. It serves as a key substrate for the enzymatic incorporation of azide-modified sugars into cellular glycoproteins and glycolipids. This allows for the selective tagging and visualization of glycoconjugates using bioorthogonal chemistry techniques, such as click chemistry. Researchers utilize it to study glycosylation processes, track glycan dynamics in living cells, and investigate the roles of glycans in cellular communication, disease progression, and immune responses. Its application is particularly valuable in proteomics and glycobiology for identifying and characterizing glycosylated biomolecules.