N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
97%
Reagent
Code: #97305
CAS Number
81246-78-8
blur_circular Chemical Specifications
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Molecular Information
Weight
763.95 g/mol
Formula
C₄₃H₄₉N₃O₈Si
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Storage & Handling
Storage
2-8°C
description Product Description
This chemical is a protected cytidine nucleoside primarily used in the synthesis of oligonucleotides, which are essential in genetic research and therapeutic applications. It features N4-benzoyl protection on the cytosine base, tert-butyldimethylsilyl (TBDMS) protection on the 3'-hydroxyl, and dimethoxytrityl (DMT) protection on the 5'-hydroxyl, ensuring specific reactions occur at desired sites during the assembly of DNA or RNA sequences. This allows for controlled stepwise synthesis and is particularly valuable in solid-phase synthesis, enabling the production of custom oligonucleotides for PCR, gene editing, and antisense therapies. Its stability and selective reactivity make it a critical component in molecular biology and pharmaceutical development.
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