Used primarily in molecular biology and biochemistry research, this compound serves as a modified nucleoside for studying DNA structure and function. It is incorporated into oligonucleotides to investigate the effects of nucleoside modifications on DNA stability, replication, and interactions with proteins. The iodine atom at the 7-position makes it useful for X-ray crystallography studies, enabling detailed structural analysis of DNA. Additionally, it is employed in the development of antisense oligonucleotides and probes for diagnostic applications, leveraging its unique properties to enhance specificity and binding affinity. Its modified structure also aids in exploring enzymatic mechanisms, particularly those involving DNA polymerases and nucleases.