5'-O-DMT-N2-(dimethylamino)methylidene-2'-deoxyguanosine
98%
Reagent
Code: #64959
CAS Number
40094-22-2
blur_circular Chemical Specifications
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Molecular Information
Weight
624.7 g/mol
Formula
C₃₄H₃₆N₆O₆
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Registry Numbers
MDL Number
MFCD01630994
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Storage & Handling
Storage
2-8℃
description Product Description
Used primarily in oligonucleotide synthesis, this chemical acts as a protected form of deoxyguanosine. The DMT (dimethyltrityl) group safeguards the 5'-hydroxyl during the synthesis process, while the dimethylamino methylidene moiety protects the exocyclic amine of the guanine base. This protection strategy is crucial for the stepwise assembly of DNA sequences in solid-phase synthesis, ensuring high yield and purity of the final oligonucleotide product. It is particularly valuable in the production of primers, probes, and therapeutic oligonucleotides for applications in research, diagnostics, and drug development.
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