5'-O-Trityl-2'-deoxyuridine
97%
Reagent
Code: #58376
CAS Number
14270-73-6
blur_circular Chemical Specifications
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Molecular Information
Weight
470.52 g/mol
Formula
C₂₈H₂₆N₂O₅
thermostat
Physical Properties
Melting Point
204-205 °C
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Storage & Handling
Density
1.300±0.06 g/cm3(Predicted)
Storage
2-8℃, dry
description Product Description
This chemical is primarily used in the synthesis of oligonucleotides, where it serves as a protected form of 2'-deoxyuridine. The trityl group acts as a protecting group for the 5'-hydroxyl, allowing selective modification of other parts of the molecule during the synthesis process. It is particularly valuable in the production of modified nucleosides and nucleotides, which are essential in the development of therapeutic agents, such as antiviral and anticancer drugs. Additionally, it plays a role in research applications, including the study of DNA repair mechanisms and the development of nucleic acid-based diagnostics. Its stability and ease of deprotection make it a useful intermediate in organic and medicinal chemistry.
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