2'-deoxy-2'-fluoro-2'-C-methyluridine

10mM in DMSO

Reagent Code: #157804
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CAS Number 863329-66-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 260.22 g/mol
Formula C₁₀H₁₃FN₂O₅
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MDL Number MFCD19982668
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in antiviral therapy, particularly in the treatment of hepatitis C virus (HCV) infections. It acts as a nucleoside analog that inhibits viral RNA replication by targeting the viral RNA-dependent RNA polymerase. Once phosphorylated inside host cells, the compound incorporates into the growing RNA chain, causing premature termination due to its modified sugar moiety. This mechanism reduces viral load and supports clearance of HCV. It has been explored as a key component in combination therapies to improve treatment efficacy and reduce the likelihood of drug resistance. Its structural modifications enhance metabolic stability and selectivity for viral enzymes over host cell polymerases, contributing to a favorable safety profile.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿3,560.00

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