5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
98%
Reagent
Code: #58370
CAS Number
163759-97-5
blur_circular Chemical Specifications
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Molecular Information
Weight
804.86 g/mol
Formula
C₄₂H₅₃N₄O₁₀P
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Storage & Handling
Storage
2-8℃
description Product Description
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of genetic research and therapeutic development. It serves as a key building block in the production of modified RNA molecules, specifically incorporating a 2'-O-(2-methoxyethyl) modification on the uridine nucleoside to enhance stability and binding affinity. Its application is crucial in the development of antisense oligonucleotides, siRNA, and other RNA-based therapeutics, which are used to target and regulate gene expression in various diseases, including cancer and genetic disorders. The protective groups, such as DMT and CE, ensure precise control during the synthesis process, allowing for the efficient assembly of complex RNA structures.
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