Used in solid-phase oligonucleotide synthesis to introduce a dimethoxytrityl-protected deoxyguanosine with a specific base modification, enabling the construction of customized DNA sequences for research in molecular biology, genomics, and diagnostic probe development. Its phosphoramidite group ensures efficient coupling, while the DMT protection allows for stepwise chain elongation and purification monitoring in automated DNA synthesizers. Commonly applied in the production of primers, probes, and modified nucleic acids for SNP detection, PCR, and antisense technologies.