Used as a specialized reagent in organic synthesis, particularly in the preparation of phosphite intermediates for nucleotide and oligonucleotide synthesis. Its structure allows for selective phosphorylation reactions, making it valuable in the development of modified DNA or RNA strands for research and therapeutic applications. The presence of the nitrophenyl group enhances photolability, enabling light-controlled activation in advanced synthetic strategies such as photoremovable protecting group chemistry. Commonly employed in solid-phase synthesis and combinatorial chemistry due to its stability and reactivity under mild conditions.