Used in solid-phase oligonucleotide synthesis to introduce modified nucleosides into DNA strands. The 8-amino group provides a reactive handle for post-synthesis labeling with fluorescent dyes, biotin, or other functional groups, enabling applications in molecular probing, diagnostics, and fluorescence-based detection assays. Its phosphoramidite group ensures efficient coupling during automated synthesis, making it valuable for creating labeled probes, primers, and modified DNA for research in genomics and nucleic acid chemistry.