This chemical is primarily used in the synthesis of modified nucleosides, which are crucial in the development of oligonucleotides for therapeutic and diagnostic applications. Its modifications, such as the 2'-fluoro group and the 4'-hydroxymethyl group, enhance the stability and binding affinity of the resulting oligonucleotides, making it valuable in the design of antisense oligonucleotides and small interfering RNA (siRNA) for gene silencing therapies. Additionally, the TBS and TBDPS protecting groups ensure selective reactivity during synthetic processes, enabling precise construction of complex nucleic acid analogs. This compound is particularly significant in research focused on antiviral and anticancer drug development, where modified nucleosides play a key role in targeting specific genetic pathways.