7-TFA-ap-7-deaza-2',3'-dideoxyadenosine
97%
Reagent
Code: #58393
CAS Number
114748-71-9
blur_circular Chemical Specifications
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Molecular Information
Weight
383.33 g/mol
Formula
C₁₆H₁₆F₃N₅O₃
thermostat
Physical Properties
Melting Point
167-169 °C(Solv: ethyl ether (60-29-7))
Boiling Point
650.9±55.0 °C(Predicted)
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Storage & Handling
Density
1.58±0.1 g/cm3(Predicted)
Storage
2-8℃
description Product Description
This compound is primarily utilized in the field of medicinal chemistry and biochemistry, particularly in the development of nucleoside analogs. It serves as a key intermediate in the synthesis of antiviral and anticancer agents. Its structural modifications, such as the 7-deaza and 2',3'-dideoxy features, enhance its ability to inhibit viral replication by interfering with the viral polymerase activity. Researchers also employ it in studies focused on understanding the mechanisms of nucleotide incorporation and DNA/RNA synthesis. Additionally, its trifluoroacetyl (TFA) group aids in improving the stability and bioavailability of the compound during experimental applications.
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