5-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoro-b-D-arabinofuranosyl-2'-deoxyadenine
97%
Reagent
Code: #48442
CAS Number
226415-08-3
science Other reagents with same CAS 226415-08-3
blur_circular Chemical Specifications
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Molecular Information
Weight
675.7 g/mol
Formula
C₃₈H₃₄FN₅O₆
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Registry Numbers
MDL Number
MFCD15145200
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Storage & Handling
Storage
2-8℃
description Product Description
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. Its role is crucial in the preparation of modified DNA strands, where the 2'-fluoro modification enhances the stability and binding affinity of the oligonucleotides. The dimethoxytrityl (DMT) group serves as a protective group during the synthesis process, allowing for selective deprotection and elongation of the oligonucleotide chain. The benzoyl group protects the adenine base, ensuring the correct sequence assembly. This chemical is instrumental in developing therapeutic oligonucleotides, such as antisense drugs and siRNA, which are used to target and modulate gene expression in various diseases. Additionally, its application extends to diagnostic tools, where it aids in the creation of probes for detecting specific genetic sequences.
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